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Melanotan 1 (afamelanotide, MT-1) is a linear synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that acts as a potent and selective MC1R (melanocortin-1 receptor) agonist. Unlike Melanotan 2, which non-selectively activates MC1R, MC3R, MC4R, and MC5R, Melanotan 1’s selectivity for MC1R makes it a valuable research tool for isolating melanocortin-1 receptor biology from the broader melanocortin receptor system. Afamelanotide has been examined extensively in controlled clinical research on MC1R-mediated photoprotection, providing a robust research dataset. This 10mg HA (High Affinity) vial provides research-grade Melanotan 1 at ≥99% purity, HPLC and MS/MS verified per batch.
Phase 3 randomized controlled trials of afamelanotide examined light exposure tolerance in erythropoietic protoporphyria (EPP) research cohorts — validating MC1R-mediated photoprotection as a real biological effect. Research applications for MT-1 span photoprotection biology, melanogenesis studies, wound healing research (MC1R is expressed on keratinocytes and fibroblasts), anti-inflammatory research, and comparative melanocortin receptor studies where MC1R-specific activity must be isolated from MC4R-mediated CNS effects.
All Melanotan 1 vials are third-party tested by independent ISO-certified laboratories. HPLC and MS/MS validation performed per batch. COA available on request.
For research and laboratory use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
Melanotan 1 HA 10mg — Research Grade MC1R Agonist
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