Melanotan 1 HA 10mg Research Peptide
Melanotan 1 (afamelanotide, MT-1) is a linear synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that acts as a potent and selective MC1R (melanocortin-1 receptor) agonist. Unlike Melanotan 2, which non-selectively activates MC1R, MC3R, MC4R, and MC5R, Melanotan 1’s selectivity for MC1R makes it a valuable research tool for isolating melanocortin-1 receptor biology from the broader melanocortin receptor system. Notably, afamelanotide has received regulatory approval in Europe (Scenesse) for the prevention of phototoxicity in adults with erythropoietic protoporphyria — providing a robust clinical research dataset. This 10mg HA (High Affinity) vial provides research-grade Melanotan 1 at ≥99% purity, HPLC and MS/MS verified per batch.
Research Background
The European regulatory approval of afamelanotide (Scenesse) for erythropoietic protoporphyria (EPP) was supported by Phase 3 randomized controlled trials demonstrating significantly increased pain-free light exposure time in EPP patients — validating MC1R-mediated photoprotection as a real biological effect. Research applications for MT-1 span photoprotection biology, melanogenesis studies, wound healing research (MC1R is expressed on keratinocytes and fibroblasts), anti-inflammatory research, and comparative melanocortin receptor studies where MC1R-specific activity must be isolated from MC4R-mediated CNS effects.
Compound Specifications
- Format: Lyophilized powder (high affinity formulation)
- Purity: ≥99% (HPLC verified)
- Quantity: 10mg per vial
- Storage: −20°C, protected from light
- CAS Number: 75921-69-6
- Molecular Weight: 1646.9 Da
Certificate of Analysis
All Melanotan 1 vials are third-party tested by independent ISO-certified laboratories. HPLC and MS/MS validation performed per batch. COA available on request.
For research and laboratory use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
