S-31 (Elamipretide) 10mg Research Peptide
S-31, also known as Elamipretide or MTP-131, is a synthetic tetrapeptide (D-Arg-2′6′-Dmt-Lys-Phe-NH2) developed by Stealth BioTherapeutics that selectively concentrates at cardiolipin in the inner mitochondrial membrane. It is one of the most clinically advanced mitochondria-targeting peptides in research, having progressed through Phase 2 and Phase 3 human trials across multiple indications including heart failure, primary mitochondrial myopathy, and renal ischemia. This 10mg vial provides research-grade S-31 at ≥99% purity, HPLC and MS/MS verified per batch.
Research Background
S-31’s clinical development profile is unusually robust for a research peptide. The PROGRESS-HF Phase 2 trial demonstrated improvements in left ventricular end-systolic volume in heart failure patients. A Phase 2 trial in primary mitochondrial myopathy showed significant improvements in 6-minute walk test distance and patient-reported fatigue. Preclinical models across aging, sarcopenia, renal ischemia, and neurodegenerative disease contexts have also generated consistent data supporting its mitochondrial protective effects.
Compound Specifications
- Format: Lyophilized powder
- Purity: ≥99% (HPLC verified)
- Quantity: 10mg per vial
- Storage: −20°C, protected from light
- Sequence: D-Arg-2′6′-Dmt-Lys-Phe-NH2
Certificate of Analysis
All S-31 vials are third-party tested by independent ISO-certified laboratories. HPLC and MS/MS validation performed per batch. COA available on request.
For research and laboratory use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
